Department of Medical Genetics Print

Address: 61022, Kharkiv

Pravda Avenue 13

tel./fax: (057) 705-16-74

E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it


HEAD OF DEPARTMENT

M.D., laureate of state prize of President of Ukraine in the area of science and technics for young scientists


STAFF OF THE DEPARTMENT

Responsible: for scientific work – M.D., professor, Y. B. Grechanina,

for treatment work – E.P. Zdubskaya, Candidate of Medical Science, A.P.;

for postgraduate – L.V. Molodan, Candidate of Medical Science, A.P.;

for educational work – E. V. Bugaeva, Candidate of Medical Science, A.P.;

Assistants: O.A. Efremova, S.V. Beletskaya.

Research staff: I.A. Volobueva, M.V. Kanyuka.

Senior laborants: O.B. Khmil

Laborant: E.A. Martemyanova


ACADEMIC WORK

The department of medical genetics of KNMU – the first independent department of genetics in Ukraine. It was founded in 2000, from 2003 is the fundamental department of medical genetics in the country. Here, the course of “Medical genetics” is carried out for students of 5th course of medical faculties, as well as an optional course for students, 3th course “Modern methods of genetic diagnosis”. From 2013, the department began training masters in the field "laboratory diagnosis".


Y.B. Grechanina

The Department traines interns and doctors of different specialties on a course of improvement "Current issues of medical genetics." Department of Medical Genetics was licensed for cycles of specialization "Medical Genetics", which started in 2011.


Modern technologies are widely used in educational process. Multimedia course of lectures on medical genetics was developed. The department has telemedical equipment that allows to conduct clinical demonstrations of patients to students.

The book “Medical genetics” was published (in Ukrainian and Russian languages).

The educational program “Roshe Education” and electronic catalogue of inherent diseases are used for English-speaking students.


At the department since the early days of its establishment functions Small Genetic Academy (SGA) scientific sessions which are held annually during international congresses and scientific conferences on medical genetics, and since 2004 - also during the annual All-Ukrainian Student Olympiad of medical genetics.


DIRECTIONS OF SCIENTIFIC INVESTIGATIONS

Priority direction of research is the diagnosis of "orphan" (rare) diseases, hereditary metabolic diseases, mitochondrial diseases, breach in the system of folate cycle, and also modern methods of diagnosis and three-stage prevention of inborn and inherent pathology. Main areas of scientific research: determine correlations between genotype, phenotypic characteristics and biochemical characteristics of hereditary syndromes; diagnosis and development of effective treatments for mitochondrial diseases; diagnosis and  ways of rehabilitation of chromosomal and monogenic diseases; evaluate the effectiveness of a three-level prevention   and screening programs of  hereditary diseases; study of polymorphic gene variants of folate cycle of Ukrainians population for personal correction and prevention of cardiovascular disease.


THE MAIN SCIENTIFIC ACHIEVEMENTS

The clinical basis of the department is Kharkiv Specialized Medical Genetic Centre (KSMGC), which composes of the department and UICG KNMU a single scientific educational production association. Ukrainian Institute of Clinical Genetics of KNMU (UICG KNMU) acts since February 2006. Specialized scientific council К 64.600.05 with specialty “Genetics” works on the basis of UICG KNMU since 2007.


The department publishes a specialized journal “Clinical genetics and perinatal diagnosis”, which is included into the list HAC of Ukraine.


Coworkers of the department do a great scientific investigational work on the topic: "To prove the principles of providing effective care to patients with "orphan" (rare) disease based on clinical, genetic and epidemiological studies."


The purpose is to study the interactions of evolutionary processes in populations and individual structural and functional changes in the genome at different stages of ontogeny population of Ukraine to create high-quality system of care for "orphan" (rare) diseases.


In the 2015-2017 is planned execution of scientific investigational work on the topic: "Optimize the early diagnosis of rare hereditary diseases of the nervous system in combination with skeletal disorders by studying the clinical and genetic and molecular-genetic disorders."


3 Doctoral Dissertations, 20 Ph.D. thesis were made under the guidance of Professor E.Y. Grechanina. 3 Doctoral Dissertations and 4 Ph.D. Thesis are prepared for defense.



TREATMENT WORK

At the Department of Medical Genetics annually held international congresses and scientific conferences devoted to modern methods of diagnosis, treatment and prevention of hereditary diseases. Professor E.Y. Grechanina consults patients all the time and is the head of Consilium, with international participation.


Meetings of expert consultative council, which includes A.P. and chiefs of the department of KSMGC, are conducted on the basis of UICG KNMU. Teachers of the department conduct a great consultative and treatment work not only on the basis of KSMGC, but also in other treatment institutions of Kharkiv and Kharkiv region (maternity homes, hospitals, research institutions, orphanages, etc.). Mobile team gives consultative treatment help to countryfolk, families with many children, families of liquidators of the Chernobyl accident, adult patients with PKU and more.


Department staff collaborates with the Laboratory of Molecular and enzymatic diagnosis USA and Germany. Professor O. Grechanina and teachers of the department are members of the World Association of metabolists SSIEM (Society for the study of inborn errors of metabolism). Teaching Staff regularly take part in international scientific forums (Netherlands, France, Japan, Germany, Portugal, Lithuania, Czech Republic, Switzerland).


The results of work the Department of Medical Genetics introduced into the practice of health care institutions in the city and region, allowing a positive impact on the quality of diagnosis, treatment and prevention of hereditary diseases.